VYZR Care · Ward 4 West · synthetic population · in-memory · engine rpp-0.4.0

Predictive overview

7 of 12 patients show an emerging adverse trajectory · 4 urgent · 2 concerning · 1 watch/minor · 5 stable

VYZR Care RPP EngineRecognition · Prediction · Prevention · deterministic · rpp-0.4.0

Demo dataset

2,009 observations12 patients · in-memory · run 0 ms

Recognitionpatterns

Predictiontime horizons

Preventioncare options

Last engine run: Sep 25 14:43
Patients analysed: 12
Patterns detected: 17 · 6 interruptive
Data freshness: newest 1m ago

Synthetic demonstration · clinician-controlled output · every finding traces to raw observations

Sim clock Sep 25 14:43

Add observations

Solid line observed at real timestamps · dashed line projected with uncertainty band · shaded band = reference range

R. Okafor

Bed 04 · 78M · day 4 · sepsis

Urgent · Rapidly worseningHighest concern · rank #1 · priority 514

Pattern recognized · last 2 d

Multisystem deterioration

Oxygen requirement 0.7 → 3.7 → 4.5 L/min over 40h; respiratory rate 18 → 25 → 27 /min over 44h; systolic pressure 128 → 100 → 97 mmHg over 44h; heart rate 85 → 103 → 106 /min over 48h; creatinine 0.90 → 1.20 → 1.50 mg/dL over 47h. 7 signals across 3 systems (respiratory, circulatory, renal) are moving in the adverse direction within the same window. Individually each change is modest; together they describe one trajectory.

Pattern strength84/100 · higher evidence

Experimental explainable index, not a probability. 7 of 10 expected signals available 99 measurements across supporting signals

Supplemental oxygen · real timestampsProjected · 6h

What may happen next

If the current slope continues: SBP ≈ 89 (84–93 mmHg) at 6h, crossing SBP 90 mmHg in ~5h; O₂ ≈ 5.8 (5.2–6.4 L/min) at 6h, crossing 6 L/min in ~8h; RR ≈ 29 (28–30 /min) at 6h, crossing RR 30/min in ~8h.

Higher evidence quality: several concordant, fresh, repeated measurements. Still a linear extrapolation, not a forecast of outcome.

Consider next

Consider a single unifying driver — sepsis, hypovolaemia/bleeding, cardiogenic failure, or a drug effect — rather than treating 7 separate problems.

D. Whitfield

Bed 11 · 71M · day 3 · AKI

Urgent · Rapidly worseningrank #2 · priority 514

Pattern recognized · last 3 d

Evolving renal injury

Creatinine 1.30 → 1.80 → 2.20 → 2.60 mg/dL over 45h (2.6× known baseline 1.00 mg/dL); urine output 56 → 29 → 27 → 25 mL/h over 40h; potassium 4.4 → 4.9 → 5.4 mmol/L over 45h. Rising creatinine with falling urine output is a concordant renal trajectory.

Pattern strength84/100 · higher evidence

Creatinine · real timestampsProjected · 6h

What may happen next

If the current slope continues: Cr ≈ 2.86 (2.75–2.98 mg/dL) at 6h; UO ≈ 15 (9–21 mL/h) at 6h, crossing <20 mL/h in ~1h.

Higher evidence quality: several concordant, fresh, repeated measurements. Still a linear extrapolation, not a forecast of outcome.

Consider next

Consider pre-renal hypoperfusion (falling output supports this, hypotension, dehydration, sepsis), nephrotoxic exposure, and obstruction.

J. Osei

Bed 05 · 69F · day 8 · pneumonia

Urgent · Rapidly worseningrank #3 · priority 502

Pattern recognized · last 2 d

Possible blood loss

Haemoglobin 12.1 → 10.9 → 9.6 g/dL over 46h (−2.5 g/dL); heart rate 82 → 95 → 100 → 109 /min over 44h; systolic pressure 126 → 110 → 105 → 104 mmHg over 48h. Falling haemoglobin with a compensatory circulatory response suggests active loss rather than dilution. Patient is anticoagulated (recorded context).

Pattern strength72/100 · higher evidence

Hemoglobin · real timestampsProjected · 6h

What may happen next

If the current slope continues: Hb ≈ 9.2 (8.8–9.5 g/dL) at 6h; HR ≈ 121 (116–127 /min) at 6h, crossing HR 130/min in ~13h; SBP ≈ 97 (93–102 mmHg) at 6h, crossing SBP 100 mmHg in ~4h.

Higher evidence quality: several concordant, fresh, repeated measurements. Still a linear extrapolation, not a forecast of outcome.

Consider next

Consider gastrointestinal, procedural/surgical-site, retroperitoneal and intramuscular sources; consider haemodilution and haemolysis as alternatives.

K. Lindqvist

Bed 07 · 48M · day 3 · AKI

Urgent · Rapidly worseningrank #4 · priority 485

Pattern recognized · last 2 d

Systemic infection trajectory

Temperature 37.3 → 38.6 → 38.7 °C over 44h; heart rate 85 → 106 → 110 /min over 44h; respiratory rate 16 → 21 → 22 /min over 47h; white cells 11.2 → 14.8 → 18.1 ×10⁹/L over 45h; CRP 40 → 120 → 190 mg/L over 45h; lactate 1.2 → 1.9 mmol/L over 45h; systolic pressure 128 → 114 → 114 mmHg over 43h. Inflammatory markers are moving with a physiological response — the pattern is systemic, not just a lab value. Occurring despite current antibiotic therapy (recorded context).

Pattern strength75/100 · higher evidence

Temperature · real timestampsProjected · 24h

What may happen next

If the current slope continues: HR ≈ 133 (127–138 /min) at 24h, crossing HR 130/min in ~21h; Temp ≈ 39.5 (39.3–39.8 °C) at 12h; SBP ≈ 105 (99–112 mmHg) at 24h.

Higher evidence quality: several concordant, fresh, repeated measurements. Still a linear extrapolation, not a forecast of outcome.

Consider next

Consider treatment failure or resistant organism, a second source, line/catheter infection, and non-infective mimics (drug fever, thrombosis).

L. Marchetti

Bed 09 · 64F · day 6 · pneumonia

Concerning · Rapidly worseningrank #5 · priority 388

Pattern recognized · last 3 d

Progressive sodium decline

Sodium 138 → 133 → 127 mmol/L over 47h (−11 mmol/L) at ≈ −6 mmol/L per 24h, falling on 3 consecutive samples. The concern is the rate and persistence of the fall, not one low value.

Pattern strength68/100 · moderate evidence

Sodium · real timestampsProjected · 12h

What may happen next

If the current slope continues: Na⁺ ≈ 124 (123–125 mmol/L) at 12h, crossing severe hyponatremia (<125) in ~8h.

Moderate evidence. Linear extrapolation of recent slope; interventions or a new measurement will change the projection.

Consider next

Consider volume status, hypotonic fluid intake, SIADH triggers (pain, nausea, medications), diuretics, and adrenal/thyroid causes.

S. Nakamura

Bed 06 · 67M · day 7 · COPD

Concerning · Worseningrank #6 · priority 359

Pattern recognized · last 2 d

Rising respiratory burden

Oxygen requirement 1.6 → 3.0 → 3.3 → 3.8 L/min over 44h; respiratory rate 19 → 25 → 26 → 27 /min over 44h; SpO₂ 91 → 90 → 90 → 89 % over 44h. Two or more respiratory signals are moving together — a work-of-breathing trajectory, not a single reading.

Pattern strength49/100 · higher evidence

Supplemental oxygen · real timestampsProjected · 24h

What may happen next

If the current slope continues: O₂ ≈ 6.2 (5.5–7.0 L/min) at 24h, crossing 6 L/min in ~22h; RR ≈ 33 (31–34 /min) at 24h, crossing RR 30/min in ~13h; SpO₂ ≈ 88 (87–90 %) at 24h.

Higher evidence quality: several concordant, fresh, repeated measurements. Still a linear extrapolation, not a forecast of outcome.

Consider next

Consider progressive pneumonia, aspiration, pulmonary embolism, bronchospasm and atelectasis.

M. Haddad

Bed 02 · 59F · day 5 · CHF

Minor · Stablerank #7 · priority 110

Pattern recognized · last 3 d

Minor sodium drift

Sodium 134 → 133 → 132 mmol/L over 47h — a small drift at the edge of assay noise (−1 mmol/L on the last sample). Noted, not escalated: no meaningful rate, no persistence beyond noise.

Pattern strength0/100 · limited evidence

Sodium · real timestampsProjected · 24h

What may happen next

If the current slope continues: Na⁺ ≈ 131 (130–132 mmol/L) at 24h.

Limited evidence — few measurements or key inputs missing. Bands are wide and a single new value can change this picture.

Consider next

No change to routine monitoring suggested; the next scheduled sodium will confirm whether this is drift or noise.

Same analyte, different trajectory · why the engine treats them differently

Both patients have falling sodium. The engine weighs magnitude, persistence across consecutive measurements, velocity and distance from the patient's own baseline — not a single abnormal number.

M. Haddad

Bed 02 · 59F · day 5 · CHF

Minor · Stable

134 → 133 → 132mmol/L

-2 mmol/L over 47 h · 3 of 3 points shown · last 4m ago

Sodium 134 → 133 → 132 mmol/L over 47h — a small drift at the edge of assay noise (−1 mmol/L on the last sample). Noted, not escalated: no meaningful rate, no persistence beyond noise.

Pattern strength: 0 / 100
Interrupt a clinician?: No · routine review

L. Marchetti

Bed 09 · 64F · day 6 · pneumonia

Concerning · Rapidly worsening

138 → 133 → 127mmol/L

-11 mmol/L over 47 h · 3 of 4 points shown · last 12m ago

Sodium 138 → 133 → 127 mmol/L over 47h (−11 mmol/L) at ≈ −6 mmol/L per 24h, falling on 3 consecutive samples. The concern is the rate and persistence of the fall, not one low value.

Pattern strength: 68 / 100
Magnitude of change: +18
Velocity: +12.5
Acceleration: +1.7
Interrupt a clinician?: Yes · justified

Stable and recovering · intelligent silenceVisible by design · the engine stays quiet when no adverse trajectory is emerging, including stable chronic abnormalities

C. AdeyemiBed 10 · day 5 · COPDStable

No trajectory concern — stable on current observations

Routine review only · 2m ago

P. ReyesBed 08 · day 4 · cellulitisRecovering

Recovering — signals returning toward range

Routine review only · 4m ago

N. PetrovBed 12 · day 7 · sepsisRecovering

Recovering — signals returning toward range

Routine review only · 12m ago

T. BrennanBed 03 · day 6 · CHFStable

No trajectory concern — stable on current observations

Routine review only · 20m ago

Synthetic demonstration · engine output supports clinician review and is not a diagnosis, validated risk score or treatment order